The Spiraling Opioid Epidemic in America

The Spiraling Opioid Epidemic in America

Over the last 20 years, the ongoing U.S. opioid crisis has claimed tens of thousands of lives. In fact, opioid overdose deaths accounted for nearly 70% of all drug overdose deaths in 2018.

Although the damage of the opioid epidemic is well documented, what people might not know is that it has escalated in three distinct waves.

We pull the latest statistics from the UN World Drug Report 2020 to uncover the scope of the opioid crisis in the U.S., and how national drug-related death rates compare to other countries.

Three Waves of the Opioid Crisis

According to the CDC, the opioid epidemic can be traced back to the 1990s, when opioids started being over-prescribed for pain relief purposes.

  • 1990s – Wave 1
    Over-prescription of opioids for pain relief, including natural opioids, semi-synthetic opioids, and methadone. Addiction risks were widely downplayed.
  • 2010 – Wave 2
    Heroin-related overdose deaths on the rise.
  • 2013 – Wave 3
    Synthetic opioid-related deaths on the rise, particularly fentanyl and tramadol.

Here’s how that breaks down in terms of opioid-related overdose deaths over the years. Note that by the year 2018, 67% of overdose deaths involved synthetic opioids such as fentanyl.

Year Any opioids Heroin Pharmaceutical opioids Synthetic opioids
1999 8,050 1,960 3,533 730
2000 8,407 1,842 3,903 782
2001 9,496 1,779 4,935 957
2002 11,920 2,089 6,774 1,295
2003 12,940 2,080 7,839 1,400
2004 13,756 1,878 9,076 1,664
2005 14,918 2,009 10,234 1,742
2006 17,545 2,088 12,423 2,707
2007 18,516 2,399 13,676 2,213
2008 19,582 3,041 14,043 2,306
2009 20,422 3,278 14,431 2,946
2010 21,089 3,036 15,520 3,007
2011 22,784 4,397 16,111 2,666
2012 23,166 5,925 15,072 2,628
2013 25,052 8,257 13,937 3,105
2014 28,647 10,574 15,559 5,544
2015 33,091 12,989 16,028 9,580
2016 42,249 15,469 17,860 19,413
2017 47,600 15,482 17,689 28,466
2018 46,802 14,996 15,575 31,335

Overdose deaths from synthetic opioids such as fentanyl and tramadol shot up by over 4,000% between 1999-2018. This can be attributed to two things: their relative potency, and the minute quantities of each that qualify as a lethal dose.

As per the medical and legal standard, opioids are often compared to morphine. To that end, heroin is 2-5x stronger—while fentanyl is 50-100x more potent. Put another way, roughly a dime-size or 10-12mg of heroin is considered a lethal dose, compared to only 1-2mg of fentanyl.

What’s worse, fentanyl is typically mixed with other types of drugs such as heroin or cocaine to increase their effects, which is how it ends up unintentionally ingested. Between 2008-2017, drug-use disorders as a whole claimed the most healthy lives due to poor health or early deaths—measured in disability-adjusted life years (DALYs)—followed in close second by opioid use disorders.

The Death Toll of U.S. Drug Overdoses

It’s undeniable that the opioid epidemic in America has caused significant harm to communities. But how does the U.S. drug crisis compare to the same issue in other countries?

The UN Drug Report further puts these numbers into perspective by comparing drug-related deaths per million population. Note that the source also compiled the total deaths across years for selected countries.

Country (Latest Year) Latest Years of Estimate Total Deaths Rate per 1M (Aged 15-64)
🇺🇸 U.S. 2018 67,367 314.5
🇦🇺 Australia 2016-2017 3,240 202.6
🇸🇻 El Salvador 2018 765 184.5
🇨🇦 Canada 2018 4,460 179.8
🇺🇾 Uruguay 2016 264 119.4
🇮🇸 Iceland 2012-2016 23 105.2
🇸🇪 Sweden 2017 575 92.9
🇳🇿 New Zealand 2016 269 88.6
🇫🇮 Finland 2017 289 83.9
🇬🇧 UK 2017 3,547 83

With 314.5 deaths per million, the U.S. by far had the highest proportion of drug-related deaths per million people in 2018. It also had the highest overall number at 67.4K deaths.

Elephant in the Room?

Another drug rearing its head on the streets is carfentanil. Formerly developed as ‘elephant tranquilizer’, this synthetic opioid is similar in appearance to other illicit drugs such as heroin, making it indistinguishable when mixed in. However, there’s one big problem—carfentanil is 100x more potent than fentanyl itself.

In response to the continued crisis, an additional $35.7 billion was requested for counter-drug funding efforts in the FY2021 Budget. This amount is expected to go towards prevention and treatment efforts ($18.6 billion) and law enforcement efforts ($17.1 billion) both domestically and internationally.

But will these efforts properly combat the crisis, or are we already in the midst of a fourth wave of the opioid epidemic?

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